产品货号：
Z37328
中文名称：
Jak2 (Ab-570)抗体
英文名称：
Anti-Jak2 (Ab-570) Antibody (Clone#OTI2F5)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Jak2 (Ab-570) Antibody (Clone#OTI2F5) |
| 指标别名 | Janus kinase 2;JTK10;JAK2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | JAK2 |
| 克隆号 | OTI2F5 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 297-596 of human JAK2(NP_004963) produced in E.coli. |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Janus kinase 2,commanly called JAK2,is a human protein that has been implicated in signaling by members of the type II cytokine receptor family,the GM-CSF receptor family,the gp130 receptor family,and the single chain receptors.Exactly,JAK2 kinase is a member of a family of tyrosine kinases involved in cytokine receptor signaling.The JAK2 gene is mapped to 9p24.1.The JAK2 gene encodes a 1,132-amino acid protein that shares 95% sequence similarity to rat and pig Jak2.JAK2 is constitutively associated with the prolactin receptor and that it is activated and tyrosine phosphorylated upon PRL binding to the PRL receptor.JAK2,and more specifically just its intact N-terminal domain,binds to EPOR in the endoplasmic reticulum and promotes its cell surface expression.The human JAK2 is present in the nucleus of hematopoietic cells and directly phosphorylates tyr41 on histone H3. |
| Uniprot ID | O60674 |
| 基因名全称 | Janus kinase 2 |
| 蛋白名全称 | Tyrosine-protein kinase JAK2 |
| 推荐稀释比 | Western blot (WB) 1:500 |
相关搜索：Jak2 (Ab-570)抗体，Jak2 (Ab-570)单抗，Anti-Jak2 (Ab-570) Antibody (Clone#OTI2F5)